Up to 90 off textbooks at amazon canada plus free two day shipping for six months when you sign up for amazon prime for students. Buy the paperback book second generation of calcium antagonists by winifred g nayler at indigoca canadas largest bookstore free shipping and pickup in store on eligible orders. The newer dihydropyridine calcium antagonists are structurally related to nifedipine but may provide greater vascular selectivity and wider clinical utility five new dihydropyridines nisoldipine nicardipine nimodipine felodipine and nitrendipine are reviewed with regard to their preclinical pha second generation dihydropyridine calcium antagonists greater vascular selectivity and . Calcium antagonists second second generation calcium antagonists search for greater selectivity and versatility singh bn baky s nademanee k calcium antagonists have a variable specificity for cardiac and peripheral activity based on such activity these compounds new and old can be classified into 4 categories type 1 agents typified by verapamil its congeners tiapamil second generation calcium